*About the NDMA detection system
We have developed a new N-nitrosodimethylamine (NDMA) detection system, based on the research results of Associate Professor Hitoshi Kodamatani of the Graduate School of Science and Engineering at Kagoshima University. The presence of NDMA, a carcinogenic N-nitrosamine, in pharmaceuticals and reclaimed water sites, is currently a worldwide problem.
The developed system utilizes HPLCs for luminol chemiluminescence detection, making it easier to obtain ultra-sensitive detection results at several ng/L of NDMA, eliminating the need for the concentration process.

Among the system features are the following.

  1. The limit of quantitation of N-nitrosoamines is several ng/L (including N-nitrosodiethanolamine (NDELA), NDMA, N-nitrosomorpholine (NMOR), N-nitrosodiethylamine (NDEA), N-nitrosopyrrolidine (NPYR)).
  2. There is no need for the concentration process.
  3. The sample volume (per inspection) is only 1 mL.
  4. The inspection time (per inspection) is only 20 minutes.

The system was shown to be highly useful in the joint study, “Utility Validation of an Alternative Method for NDMA Analysis Requiring Less Time, Cost, and Sample Volume (Water Environment and Reuse Foundation)”, conducted by Dr. Megan Plumlee of the Orange County Water District (OCWD, CA, USA), which has the world’s largest advanced sewage treatment plant, along with Associate Professor Takahiro Fujioka of the Nagasaki University Graduate School of Engineering, and Associate Professor Hitoshi Kodamatani.

However, the system is still not widely known. Thus, as we would like to demonstrate the advantages of the system to a wide audience, we have established an N-nitrosamine sample analysis service, with the following structure.


We will ask you to describe your sample type:
We will ask you to send us a sample/s, to determine whether it/they can be properly inspected using our system (this analysis is free of charge). In addition, we will confirm the inspection method and time.
We will send you a quotation based on the inspection method and time, and the total number of samples.
If you are satisfied with the quotation, you will pay the inspection fee and send us the actual sample/s.
We will begin the inspection of your sample/s after receiving your payment and sample/s.
We will report the results within the contract period.

*Data on the Measurement of Samples Containing n-nitroso Compounds
The links below will take you to examples of analyzes we have carried out.

If you are interested in our service, please read the following before contacting us.


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